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Testosterone, not 5α-Dihydrotestosterone, Stimulates LRH-1 Leading to FSH-Independent Expression of Cyp19 and P450scc in Granulosa Cells

Androgens are crucial for normal folliculogenesis and female fertility as evidenced in androgen receptor-null and granulosa cell conditional knockout mice. It is thought, however, that the multiple effects of androgens in the ovary are mainly complementary to the actions of gonadotropins. Using prim...

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Detalhes bibliográficos
Main Authors: Wu, Yan-Guang, Bennett, Jill, Talla, Deepika, Stocco, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063088/
https://ncbi.nlm.nih.gov/pubmed/21273442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0367
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