Loss of GATA-6 and GATA-4 in Granulosa Cells Blocks Folliculogenesis, Ovulation, and Follicle Stimulating Hormone Receptor Expression Leading to Female Infertility

Single GATA-6 (G6(gcko)), GATA-4 (G4(gcko)), and double GATA-4/6 (G4/6(gcko)) granulosa cell-specific knockout mice were generated to further investigate the role of GATA transcription factors in ovarian function in vivo. No reproductive defects were found in G6(gcko) animals. G4(gcko) animals were...

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Main Authors: Bennett, Jill, Wu, Yan-Guang, Gossen, Jan, Zhou, Ping, Stocco, Carlos
格式: Artigo
語言:Inglês
出版: Endocrine Society 2012
主題:
Reproduction-Development
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339651/
https://ncbi.nlm.nih.gov/pubmed/22434075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1969
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