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Selective expression of Kras(G12D) in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

Activation of the RAS family of small G-proteins is essential for follicle stimulating hormone-induced signaling events and the regulation of target genes in cultured granulosa cells. To analyze the functions of RAS protein in granulosa cells during ovarian follicular development in vivo, we generat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Heng-Yu, Shimada, Masayuki, Liu, Zhilin, Cahill, Nicola, Noma, Noritaka, Wu, Yun, Gossen, Jan, Richards, JoAnne S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541831/
https://ncbi.nlm.nih.gov/pubmed/18506027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.020560
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