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Selective expression of Kras(G12D) in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

Activation of the RAS family of small G-proteins is essential for follicle stimulating hormone-induced signaling events and the regulation of target genes in cultured granulosa cells. To analyze the functions of RAS protein in granulosa cells during ovarian follicular development in vivo, we generat...

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Detalhes bibliográficos
Main Authors: Fan, Heng-Yu, Shimada, Masayuki, Liu, Zhilin, Cahill, Nicola, Noma, Noritaka, Wu, Yun, Gossen, Jan, Richards, JoAnne S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541831/
https://ncbi.nlm.nih.gov/pubmed/18506027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.020560
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