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Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function
The NUP98 gene encodes precursor proteins that generate two nucleoplasmically oriented nucleoporins, NUP98 and NUP96. By using gene targeting, we have selectively disrupted the murine NUP98 protein, leaving intact the expression and localization of NUP96. We show that NUP98 is essential for mouse ga...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30629/ https://ncbi.nlm.nih.gov/pubmed/11248054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051631598 |
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