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The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency

Amyloid fibers in human semen known as SEVI (Semen-derived Enhancer of Viral Infection) dramatically increase the infectivity of HIV and other enveloped viruses, which appears to be linked to the promotion of bridging interactions and the neutralization of electrostatic repulsion between the host an...

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Bibliografske podrobnosti
Main Authors: Brender, Jeffrey R., Nanga, Ravi Prakash Reddy, Popovych, Nataliya, Soong, Ronald, Macdonald, Peter M., Ramamoorthy, Ayyalusamy
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062746/
https://ncbi.nlm.nih.gov/pubmed/21262195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.01.010
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