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The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency
Amyloid fibers in human semen known as SEVI (Semen-derived Enhancer of Viral Infection) dramatically increase the infectivity of HIV and other enveloped viruses, which appears to be linked to the promotion of bridging interactions and the neutralization of electrostatic repulsion between the host an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062746/ https://ncbi.nlm.nih.gov/pubmed/21262195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.01.010 |
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