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The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency

Amyloid fibers in human semen known as SEVI (Semen-derived Enhancer of Viral Infection) dramatically increase the infectivity of HIV and other enveloped viruses, which appears to be linked to the promotion of bridging interactions and the neutralization of electrostatic repulsion between the host an...

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Bibliographische Detailangaben
Hauptverfasser: Brender, Jeffrey R., Nanga, Ravi Prakash Reddy, Popovych, Nataliya, Soong, Ronald, Macdonald, Peter M., Ramamoorthy, Ayyalusamy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062746/
https://ncbi.nlm.nih.gov/pubmed/21262195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.01.010
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