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The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency

Amyloid fibers in human semen known as SEVI (Semen-derived Enhancer of Viral Infection) dramatically increase the infectivity of HIV and other enveloped viruses, which appears to be linked to the promotion of bridging interactions and the neutralization of electrostatic repulsion between the host an...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Brender, Jeffrey R., Nanga, Ravi Prakash Reddy, Popovych, Nataliya, Soong, Ronald, Macdonald, Peter M., Ramamoorthy, Ayyalusamy
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062746/
https://ncbi.nlm.nih.gov/pubmed/21262195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.01.010
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