Bacterial curli protein promotes the conversion of PAP(248-286) into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences

Fragments of prostatic acid phosphatase (PAP(248-286)) in human semen dramatically increase HIV infection efficiency by increasing virus adhesion to target cells. PAP(248-286) only enhances HIV infection in the form of amyloid aggregates termed SEVI (Semen Enhancer of Viral Infection), however monom...

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Detalhes bibliográficos
Main Authors: Hartman, Kevin, Brender, Jeffrey R., Monde, Kazuaki, Ono, Akira, Evans, Margery L., Popovych, Nataliya, Chapman, Matthew R., Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2013
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629062/
https://ncbi.nlm.nih.gov/pubmed/23638387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5
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