MECHANISM FOR NICOTINE-INDUCED UP-REGULATION OF WNT SIGNALING IN HUMAN ALVEOLAR INTERSTITIAL FIBROBLASTS

Nicotine exposure alters normal homeostatic pulmonary epithelial-mesenchymal paracrine signaling pathways, resulting in alveolar interstitial fibroblast (AIF)-to-myofibroblast (MYF) transdifferentiation. Since the AIF vs MYF phenotype is determined by the expression of Peroxisome Proliferator-Activa...

Full description

Saved in:
Bibliographic Details
Main Authors: Sakurai, Reiko, Cerny, Laura M., Torday, John S., Rehan, Virender K.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062662/
https://ncbi.nlm.nih.gov/pubmed/21133803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2010.490288
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items