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MECHANISM FOR NICOTINE-INDUCED UP-REGULATION OF WNT SIGNALING IN HUMAN ALVEOLAR INTERSTITIAL FIBROBLASTS
Nicotine exposure alters normal homeostatic pulmonary epithelial-mesenchymal paracrine signaling pathways, resulting in alveolar interstitial fibroblast (AIF)-to-myofibroblast (MYF) transdifferentiation. Since the AIF vs MYF phenotype is determined by the expression of Peroxisome Proliferator-Activa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062662/ https://ncbi.nlm.nih.gov/pubmed/21133803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2010.490288 |
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