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Synthesis and properties of oligodeoxynucleotides with an AP site at a preselected position.

A general synthesis of a deoxyoligonucleotide with an AP site at a preselected sequence is described. Deoxyuridine is introduced during routine oligonucleotide syntheses of d(TTTUTTTT) and d(AAAAGTTUAAAACAT). Treatment with uracil DNA-glycosylase produces d(TTTrTTTT), where r = deoxyribose, and d(AA...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Stuart, G R, Chambers, R W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC306260/
https://ncbi.nlm.nih.gov/pubmed/3658699
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