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Synthesis and properties of oligodeoxynucleotides with an AP site at a preselected position.
A general synthesis of a deoxyoligonucleotide with an AP site at a preselected sequence is described. Deoxyuridine is introduced during routine oligonucleotide syntheses of d(TTTUTTTT) and d(AAAAGTTUAAAACAT). Treatment with uracil DNA-glycosylase produces d(TTTrTTTT), where r = deoxyribose, and d(AA...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1987
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306260/ https://ncbi.nlm.nih.gov/pubmed/3658699 |
| Etykiety: |
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