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Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: Novel insights into the regulation of Rev nuclear import

BACKGROUND: The HIV-1 regulatory protein Rev, which is essential for viral replication, mediates the nuclear export of unspliced viral transcripts. Rev nuclear function requires active nucleocytoplasmic shuttling, and Rev nuclear import is mediated by the recognition of its Nuclear Localisation Sign...

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Библиографические подробности
Главные авторы: Gu, Lili, Tsuji, Takahiro, Jarboui, Mohamed Ali, Yeo, Geok P, Sheehy, Noreen, Hall, William W, Gautier, Virginie W
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062594/
https://ncbi.nlm.nih.gov/pubmed/21401918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-17
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