Increased Incidence of Choroid Plexus Carcinoma Due to the Germline TP53 R337H Mutation in Southern Brazil

BACKGROUND: Choroid plexus carcinomas (CPC) are rare tumors predominantly found in children. Given the high frequency of the germline R337H mutation in the TP53 gene in southern Brazil, we have evaluated the frequency of the R337H mutation in families with CPC in children. METHODOLOGY/PRINCIPAL FIND...

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Detalhes bibliográficos
Main Authors: Custodio, Gislaine, Taques, Guilherme R., Figueiredo, Bonald C., Gugelmin, Elizabeth S., Oliveira Figueiredo, Mirna M., Watanabe, Flora, Pontarolo, Roberto, Lalli, Enzo, Torres, Luiz Fernando Bleggi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062554/
https://ncbi.nlm.nih.gov/pubmed/21445348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018015
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