Llwytho...

Effector analogues detect varied allosteric roles for conserved protein-effector interactions in pyruvate kinase isozymes

The binding site for allosteric inhibitor (amino acid) is highly conserved between human liver pyruvate kinase (hL-PYK) and the rabbit muscle isozyme (rM(1)-PYK). To detail similarities/differences in the allosteric function of these two homologs, we quantified the binding of 45 amino acid analogues...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alontaga, Aileen Y., Fenton, Aron W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062439/
https://ncbi.nlm.nih.gov/pubmed/21261284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200052e
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!