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Transcriptional inhibition by DNA torsional stress

Most genome transactions are favored by DNA (−) torsional stress, i.e., unconstrained unwinding or supercoiling of DNA. A question raised here is whether DNA (+) torsional stress, which precludes DNA unwinding, could also be relevant in gene regulation. Such DNA twist dynamics could be determined by...

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Detalhes bibliográficos
Autor principal: Roca, Joaquim
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062399/
https://ncbi.nlm.nih.gov/pubmed/21468234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.2.14807
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