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Transcription-induced DNA supercoiling: New roles of intranucleosomal DNA loops in DNA repair and transcription

RNA polymerase II (Pol II) transcription through chromatin is accompanied by formation of small intranucleosomal DNA loops. Pol II captured within a small loop drives accumulation of DNA supercoiling, facilitating further transcription. DNA breaks relieve supercoiling and induce Pol II arrest, allow...

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書目詳細資料
發表在:Transcription
Main Authors: Gerasimova, N. S., Pestov, N. A., Kulaeva, O. I., Clark, D. J., Studitsky, V. M.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984681/
https://ncbi.nlm.nih.gov/pubmed/27115204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1182240
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