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Transcription-induced DNA supercoiling: New roles of intranucleosomal DNA loops in DNA repair and transcription
RNA polymerase II (Pol II) transcription through chromatin is accompanied by formation of small intranucleosomal DNA loops. Pol II captured within a small loop drives accumulation of DNA supercoiling, facilitating further transcription. DNA breaks relieve supercoiling and induce Pol II arrest, allow...
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| Publicado no: | Transcription |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4984681/ https://ncbi.nlm.nih.gov/pubmed/27115204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1182240 |
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