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Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators
Indoleamine 2,3-dioxygenase (IDO) is an immunoregulatory enzyme that is implicated in suppressing T-cell immunity in normal and pathologic settings. Here, we describe that spontaneous cytotoxic T-cell reactivity against IDO exists not only in patients with cancer but also in healthy persons. We show...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062329/ https://ncbi.nlm.nih.gov/pubmed/21079151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288498 |
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