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Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

Indoleamine 2,3-dioxygenase (IDO) is an immunoregulatory enzyme that is implicated in suppressing T-cell immunity in normal and pathologic settings. Here, we describe that spontaneous cytotoxic T-cell reactivity against IDO exists not only in patients with cancer but also in healthy persons. We show...

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Hlavní autoři: Sørensen, Rikke Bæk, Hadrup, Sine Reker, Svane, Inge Marie, Hjortsø, Mads Christian, thor Straten, Per, Andersen, Mads Hald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062329/
https://ncbi.nlm.nih.gov/pubmed/21079151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288498
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