Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

The transcription factor PU.1 occupies a central role in controlling myeloid and early B-cell development, and its correct lineage-specific expression is critical for the differentiation choice of hematopoietic progenitors. However, little is known of how this tissue-specific pattern is established....

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Leddin, Mathias, Perrod, Chiara, Hoogenkamp, Maarten, Ghani, Saeed, Assi, Salam, Heinz, Sven, Wilson, Nicola K., Follows, George, Schönheit, Jörg, Vockentanz, Lena, Mosammam, Ali M., Chen, Wei, Tenen, Daniel G., Westhead, David R., Göttgens, Berthold, Bonifer, Constanze, Rosenbauer, Frank
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062295/
https://ncbi.nlm.nih.gov/pubmed/21239694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-302976
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki