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Chlorzoxazone, an SK channel activator used in humans, reduces excessive alcohol intake in rats

BACKGROUND: Alcoholism imposes a tremendous social and economic burden. There are relatively few pharmacological treatments for alcoholism, with only moderate efficacy, and there is considerable interest in identifying additional therapeutic options. Alcohol exposure alters SK-type potassium channel...

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Hlavní autoři: Hopf, F. Woodward, Simms, Jeffrey A., Chang, Shao-Ju, Seif, Taban, Bartlett, Selena E., Bonci, Antonello
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062269/
https://ncbi.nlm.nih.gov/pubmed/21195386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.11.011
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