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Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence

The cellular mechanisms underlying pathological alcohol seeking remain poorly understood. Here, we show an enhancement of nucleus accumbens (NAcb) core action potential firing ex vivo after protracted abstinence from alcohol but not sucrose self-administration. Increased firing is associated with re...

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Detalhes bibliográficos
Main Authors: Hopf, F. Woodward, Bowers, M. Scott, Chang, Shao-Ju, Chen, Billy T., Martin, Miguel, Seif, Taban, Cho, Saemi L., Tye, Kay, Bonci, Antonello
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847608/
https://ncbi.nlm.nih.gov/pubmed/20223203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.02.015
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