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Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence

The cellular mechanisms underlying pathological alcohol seeking remain poorly understood. Here, we show an enhancement of nucleus accumbens (NAcb) core action potential firing ex vivo after protracted abstinence from alcohol but not sucrose self-administration. Increased firing is associated with re...

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Sonraí Bibleagrafaíochta
Main Authors: Hopf, F. Woodward, Bowers, M. Scott, Chang, Shao-Ju, Chen, Billy T., Martin, Miguel, Seif, Taban, Cho, Saemi L., Tye, Kay, Bonci, Antonello
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847608/
https://ncbi.nlm.nih.gov/pubmed/20223203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.02.015
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