Nucleus accumbens AGS3 expression drives ethanol seeking through Gβγ

Approximately 90% of alcoholics relapse within 4 years, in part because of an enhanced motivation to seek alcohol (EtOH). A novel G protein modulator (Gpsm1/AGS3) was up-regulated in the rat nucleus accumbens core (NAcore) but not in other limbic nuclei during abstinence from operant EtOH self-admin...

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Autores principales: Bowers, M. Scott, Hopf, F. Woodward, Chou, Jonathan K., Guillory, Anitra M., Chang, Shao-Ju, Janak, Patricia H., Bonci, Antonello, Diamond, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527946/
https://ncbi.nlm.nih.gov/pubmed/18719114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706999105
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