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Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake

Compulsive drinking despite serious adverse medical, social and economic consequences is a characteristic of alcohol use disorders in humans. Although frontal cortical areas have been implicated in alcohol use disorders, little is known about the molecular mechanisms and pathways that sustain aversi...

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Detalhes bibliográficos
Main Authors: Seif, Taban, Chang, Shao-Ju, Simms, Jeffrey A, Gibb, Stuart L, Dadgar, Jahan, Chen, Billy T, Harvey, Brandon K, Ron, Dorit, Messing, Robert O, Bonci, Antonello, Hopf, F Woodward
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939030/
https://ncbi.nlm.nih.gov/pubmed/23817545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3445
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