Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer

We have used a gene expression array–based strategy to identify the methylation of tissue factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in human colorectal cancers (CRC). TFPI2 belongs to the recently described group of embryonic cell Polycomb group (PcG)...

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Main Authors: Glöckner, Sabine C., Dhir, Mashaal, Yi, Joo Mi, McGarvey, Kelly E., Van Neste, Leander, Louwagie, Joost, Chan, Timothy A., Kleeberger, Wolfram, de Bruïne, Adriaan P., Smits, Kim M., Khalid-de Bakker, Carolina A.J., Jonkers, Daisy M.A.E., Stockbrügger, Reinhold W., Meijer, Gerrit A., Oort, Frank A., Iacobuzio-Donahue, Christine, Bierau, Katja, Herman, James G., Baylin, Stephen B., Van Engeland, Manon, Schuebel, Kornel E., Ahuja, Nita
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062162/
https://ncbi.nlm.nih.gov/pubmed/19435926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0142
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