Point mutations and sequence variability in proteins: Redistributions of preexisting populations
Here we study the effect of point mutations in proteins on the redistributions of the conformational substates. We show that regardless of the location of a mutation in the protein structure and of its type, the observed movements of the backbone recur largely at the same positions in the structures...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248045/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051399098 |
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