A census of glutamine/asparagine-rich regions: Implications for their conserved function and the prediction of novel prions
Glutamine/asparagine (Q/N)-rich domains have a high propensity to form self-propagating amyloid fibrils. This phenomenon underlies both prion-based inheritance in yeast and aggregation of a number of proteins involved in human neurodegenerative diseases. To examine the prevalence of this phenomenon,...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.22.11910 |
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