Prion strains depend on different endocytic routes for productive infection
Abstract Prions are unconventional agents composed of misfolded prion protein that cause fatal neurodegenerative diseases in mammals. Prion strains induce specific neuropathological changes in selected brain areas. The mechanism of strain-specific cell tropism is unknown. We hypothesised that prion...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2017-07-01
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| Seria: | Scientific Reports |
| Dostęp online: | https://doi.org/10.1038/s41598-017-07260-2 |
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