Silencing Mitogen-Activated Protein Kinase-Activated Protein Kinase-2 Arrests Inflammatory Bone Loss

p38 mitogen-activated protein kinases (MAPKs) are critical for innate immune signaling and subsequent cytokine expression in periodontal inflammation and bone destruction. In fact, previous studies show that systemic p38 MAPK inhibitors block periodontal disease progression. However, development of...

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Detalhes bibliográficos
Main Authors: Li, Qiyan, Yu, Hong, Zinna, Robert, Martin, Kylie, Herbert, Bethany, Liu, Angen, Rossa, Carlos, Kirkwood, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Inflammation, Immunopharmacology, and Asthma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061533/
https://ncbi.nlm.nih.gov/pubmed/21139061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.172395
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