Silencing Mitogen-Activated Protein Kinase-Activated Protein Kinase-2 Arrests Inflammatory Bone Loss

p38 mitogen-activated protein kinases (MAPKs) are critical for innate immune signaling and subsequent cytokine expression in periodontal inflammation and bone destruction. In fact, previous studies show that systemic p38 MAPK inhibitors block periodontal disease progression. However, development of...

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Hlavní autoři: Li, Qiyan, Yu, Hong, Zinna, Robert, Martin, Kylie, Herbert, Bethany, Liu, Angen, Rossa, Carlos, Kirkwood, Keith L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
Inflammation, Immunopharmacology, and Asthma
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061533/
https://ncbi.nlm.nih.gov/pubmed/21139061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.172395
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