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Anti-inflammatory Effect of MAPK Phosphatase-1 Local Gene Transfer in Inflammatory Bone Loss
Alveolar bone loss associated with periodontal diseases is the result of osteoclastogenesis induced by bacterial pathogens. The mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP- 1) is a critical negative regulator of immune response as a key phosphatase capable of dephosphorylating activat...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086452/ https://ncbi.nlm.nih.gov/pubmed/21068780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.139 |
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