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Anti-inflammatory Effect of MAPK Phosphatase-1 Local Gene Transfer in Inflammatory Bone Loss

Alveolar bone loss associated with periodontal diseases is the result of osteoclastogenesis induced by bacterial pathogens. The mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP- 1) is a critical negative regulator of immune response as a key phosphatase capable of dephosphorylating activat...

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Main Authors: Yu, Hong, Li, Qiyan, Herbert, Bethany, Zinna, Robert, Martin, Kylie, Junior, Carlos Rossa, Kirkwood, Keith L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086452/
https://ncbi.nlm.nih.gov/pubmed/21068780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.139
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