Mitogen-Activated Protein Kinase 2 Signaling Shapes Macrophage Plasticity in Aggregatibacter actinomycetemcomitans-Induced Bone Loss

Aggregatibacter actinomycetemcomitans is associated with aggressive periodontal disease, which is characterized by inflammation-driven alveolar bone loss. A. actinomycetemcomitans activates the p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase 2 (MK2) stress pathways in m...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Herbert, Bethany A., Steinkamp, Heidi M., Gaestel, Matthias, Kirkwood, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203644/
https://ncbi.nlm.nih.gov/pubmed/27795356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00552-16
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