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Genetic variation in the TGF-β-signaling pathway and colon and rectal cancer risk
BACKGROUND: The TGF-β-signaling pathway is an essential regulator of many cellular process involved in carcinogenesis. Smad proteins are central to the function of TGF-β-signaling. In this study we evaluate genetic variation in TGFβ1, TGFβR1, Smad1, Smad2, Smad3, and Smad4 and risk of colon and rect...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061458/ https://ncbi.nlm.nih.gov/pubmed/21068203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0843 |
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