Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and risk of colon and rectal cancer: additional support for a TGF-β-signaling pathway

The Runt-related transcription factors (RUNX), mitogen-activated protein kinase (MAPK) 1 and eukaryotic translation initiation factor 4E (eIF4E) are potentially involved in tumorigenesis. We evaluated genetic variation in RUNX1 (40 tagSNPs), RUNX2 (19 tagSNPs), RUNX3 (9 tagSNPs), MAPK1 (6 tagSNPs),...

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Detalhes bibliográficos
Main Authors: Slattery, Martha L., Lundgreen, Abbie, Herrick, Jennifer S., Caan, Bette J., Potter, John D., Wolff, Roger K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047235/
https://ncbi.nlm.nih.gov/pubmed/21088106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq245
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