Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand-break resection and resolution of double-Holliday Junctions

The Rad2/XPG family nuclease, Exo1, functions in a variety of DNA repair pathways. During meiosis, Exo1 promotes crossing-over and thereby facilitates chromosome segregation at the first division. Meiotic recombination is initiated by programmed DNA double-strand-breaks (DSBs). Nucleolytic resection...

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Autores principales: Zakharyevich, Kseniya, Ma, Yunmei, Tang, Shangming, Hwang, Patty Yi-Hwa, Boiteux, Serge, Hunter, Neil
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061447/
https://ncbi.nlm.nih.gov/pubmed/21172664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.032
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