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Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand-break resection and resolution of double-Holliday Junctions
The Rad2/XPG family nuclease, Exo1, functions in a variety of DNA repair pathways. During meiosis, Exo1 promotes crossing-over and thereby facilitates chromosome segregation at the first division. Meiotic recombination is initiated by programmed DNA double-strand-breaks (DSBs). Nucleolytic resection...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061447/ https://ncbi.nlm.nih.gov/pubmed/21172664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.032 |
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