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Double Holliday Junctions are Intermediates of DNA Break Repair

Repair of DNA double-strand-breaks (DSBs) by homologous recombination is crucial for cell proliferation and tumor suppression. However, despite its importance, the molecular intermediates of mitotic DSB-repair remain undefined. The double Holliday Junction (dHJ), presupposed to be the central interm...

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Detalhes bibliográficos
Main Authors: Bzymek, Malgorzata, Thayer, Nathaniel H., Oh, Steve D., Kleckner, Nancy, Hunter, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851831/
https://ncbi.nlm.nih.gov/pubmed/20348905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08868
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