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G(i/o)-Coupled Receptors Compete for Signaling to Adenylyl Cyclase in SH-SY5Y Cells and Reduce Opioid-Mediated cAMP Overshoot

Organization of G protein-coupled receptors and cognate signaling partners at the plasma membrane has been proposed to occur via multiple mechanisms, including membrane microdomains, receptor oligomerization, and protein scaffolding. Here, we investigate the organization of six types of G(i/o)-coupl...

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Библиографические подробности
Главные авторы: Levitt, Erica S., Purington, Lauren C., Traynor, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061372/
https://ncbi.nlm.nih.gov/pubmed/21098043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064816
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