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G(i/o)-Coupled Receptors Compete for Signaling to Adenylyl Cyclase in SH-SY5Y Cells and Reduce Opioid-Mediated cAMP Overshoot

Organization of G protein-coupled receptors and cognate signaling partners at the plasma membrane has been proposed to occur via multiple mechanisms, including membrane microdomains, receptor oligomerization, and protein scaffolding. Here, we investigate the organization of six types of G(i/o)-coupl...

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Autori principali: Levitt, Erica S., Purington, Lauren C., Traynor, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061372/
https://ncbi.nlm.nih.gov/pubmed/21098043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064816
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