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A Serotype 5/3 Adenovirus Expressing MDA-7/IL-24 Infects Renal Carcinoma Cells and Promotes Toxicity of Agents That Increase Ros and Ceramide Levels

Agents that generate reactive oxygen species (ROS) are recognized to enhance MDA-7/IL-24 lethality. The present studies focused on clarifying how such agents enhanced MDA-7/IL-24 toxicity in renal cell carcinoma cells (RCCs). Infection of RCCs with a tropism-modified serotype 5/3 adenovirus expressi...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Park, Margaret A., Hamed, Hossein A., Mitchell, Clint, Cruickshanks, Nichola, Dash, Rupesh, Allegood, Jeremy, Dmitriev, Igor P., Tye, Gary, Ogretmen, Besim, Spiegel, Sarah, Yacoub, Adly, Grant, Steven, Curiel, David T., Fisher, Paul B., Dent, Paul
التنسيق: Artigo
اللغة:Inglês
منشور في: The American Society for Pharmacology and Experimental Therapeutics 2011
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061366/
https://ncbi.nlm.nih.gov/pubmed/21119025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069484
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