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Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery
We have determined whether an adenovirus that comprises the tail and shaft domains of a serotype 5 virus and the knob domain of a serotype 3 virus expressing MDA-7/IL-24, Ad.5/3-mda-7, more effectively infects and kills renal carcinoma cells (RCCs) compared to a serotype 5 virus, Ad.5-mda-7. RCCs ar...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Landes Bioscience
2010
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047088/ https://ncbi.nlm.nih.gov/pubmed/20948318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.12.13497 |
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