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The Pentostatin Plus Cyclophosphamide (PC) Non-myeloablative Regimen Induces Durable Host T Cell Functional Deficits and Prevents Murine Marrow Allograft Rejection

In this manuscript, we characterize for the first time an animal model of non-myeloablative bone marrow transplantation (BMT) using the purine analog pentostatin [P]. Other cohorts of mice received a distinct purine analog, fludarabine [F], which we and others have previously evaluated in non-myeloa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mariotti, Jacopo, Taylor, Justin, Massey, Paul R., Ryan, Kaitlyn, Foley, Jason, Buxhoeveden, Nicole, Felizardo, Tania C., Amarnath, Shoba, Mossoba, Miriam E., Fowler, Daniel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061246/
https://ncbi.nlm.nih.gov/pubmed/21130889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2010.11.029
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