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The biophysical and molecular basis of TRPV1 proton gating
The capsaicin receptor TRPV1, a member of the transient receptor potential family of non-selective cation channels is a polymodal nociceptor. Noxious thermal stimuli, protons, and the alkaloid irritant capsaicin open the channel. The mechanisms of heat and capsaicin activation have been linked to vo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061026/ https://ncbi.nlm.nih.gov/pubmed/21285946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.19 |
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