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Prion Protein Polymorphisms Affect Chronic Wasting Disease Progression

Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection. To test this effect, we orally inoculated 12 white-tailed deer with CWD agent. Three different PRNP alleles, wild-type (wt; glu...

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Detalhes bibliográficos
Main Authors: Johnson, Chad J., Herbst, Allen, Duque-Velasquez, Camilo, Vanderloo, Joshua P., Bochsler, Phil, Chappell, Rick, McKenzie, Debbie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060816/
https://ncbi.nlm.nih.gov/pubmed/21445256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017450
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