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Substituent Effects on Electrophilic Catalysis by the Carbonyl Group: Anatomy of the Rate Acceleration for PLP-Catalyzed Deprotonation of Glycine

First-order rate constants, determined by (1)H NMR, are reported for deuterium exchange between solvent D(2)O and the α-amino carbon of glycine in the presence of increasing concentrations of carbonyl compounds (acetone, benzaldehyde and salicylaldehyde) and at different pD and buffer concentrations...

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Autors principals: Crugeiras, Juan, Rios, Ana, Riveiros, Enrique, Richard, John P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060797/
https://ncbi.nlm.nih.gov/pubmed/21323335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110795m
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