Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
The reactivation of telomerase activity in most cancer cells supports the concept that telomerase is a relevant target in oncology, and telomerase inhibitors have been proposed as new potential anticancer agents. The telomeric G-rich single-stranded DNA can adopt in vitro an intramolecular quadruple...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051620698 |
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