Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay

The reactivation of telomerase activity in most cancer cells supports the concept that telomerase is a relevant target in oncology, and telomerase inhibitors have been proposed as new potential anticancer agents. The telomeric G-rich single-stranded DNA can adopt in vitro an intramolecular quadruple...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Mergny, Jean-Louis, Lacroix, Laurent, Teulade-Fichou, Marie-Paule, Hounsou, Candide, Guittat, Lionel, Hoarau, Magali, Arimondo, Paola B., Vigneron, Jean-Pierre, Lehn, Jean-Marie, Riou, Jean-François, Garestier, Thérèse, Hélène, Claude
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051620698
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