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Clk2 and B56β mediate insulin regulated assembly of the PP2A phosphatase holoenzyme complex on Akt
Akt mediates important cellular decisions involved in growth, survival and metabolism. The mechanisms by which Akt is phosphorylated and activated in response to growth factors or insulin have been extensively studied, but the molecular regulatory components and dynamics of Akt attenuation are poorl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060660/ https://ncbi.nlm.nih.gov/pubmed/21329884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.007 |
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