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Generation of Active Protein Phosphatase 2A Is Coupled to Holoenzyme Assembly
Protein phosphatase 2A (PP2A) is a prime example of the multisubunit architecture of protein serine/threonine phosphatases. Until substrate-specific PP2A holoenzymes assemble, a constitutively active, but nonspecific, catalytic C subunit would constitute a risk to the cell. While it has been assumed...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885835/ https://ncbi.nlm.nih.gov/pubmed/17550305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050155 |
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