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REST Regulates DYRK1A Transcription in a Negative Feedback Loop
DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) has been shown to be involved in learning and memory impairments in Alzheimer disease and Down syndrome. As a homolog of Drosophila minibrain gene, DYRK1A also plays important roles in neurodevelopment; however, the function and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060526/ https://ncbi.nlm.nih.gov/pubmed/21252229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174540 |
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