REST Regulates DYRK1A Transcription in a Negative Feedback Loop

DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) has been shown to be involved in learning and memory impairments in Alzheimer disease and Down syndrome. As a homolog of Drosophila minibrain gene, DYRK1A also plays important roles in neurodevelopment; however, the function and...

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Autors principals: Lu, Mei, Zheng, Lanlan, Han, Bo, Wang, Luanluan, Wang, Pin, Liu, Heng, Sun, Xiulian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060526/
https://ncbi.nlm.nih.gov/pubmed/21252229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174540
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