Refined Mapping of the Renal Failure Rf-3 Quantitative Trait Locus

Rf-3, a quantitative trait locus (QTL) on rat chromosome 3, affects the development of CKD in Fawn-Hooded Hypertensive (FHH) rats. This QTL spans 110 Mb and approximately 1400 genes; therefore, narrowing the position of this locus is necessary to elucidate potential candidate genes. Here, we used co...

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Bibliographic Details
Main Authors: O'Meara, Caitlin C., Lazar, Jozef, Hoffman, Matthew, Moreno, Carol, Jacob, Howard J.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2011
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060445/
https://ncbi.nlm.nih.gov/pubmed/21127141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060661
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