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Refined Mapping of a Hypertension Susceptibility Locus on Rat Chromosome 12

Previously, we found that transferring 6.1 Mb of SS chromosome 12 (13.4-19.5 Mb) onto the consomic SS-12(BN) background significantly elevated mean arterial pressure in response to an 8% NaCl diet (178±7 vs. 144±2 mmHg; P<0.001). Using congenic mapping, we have now narrowed the blood pressure loc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Prisco, Sasha Z., Prokop, Jeremy W., Sarkis, Allison B., Yeo, Nan Cher, Hoffman, Matthew J., Hansen, Colin C., Jacob, Howard J., Flister, Michael J., Lazar, Jozef
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162822/
https://ncbi.nlm.nih.gov/pubmed/25001272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03550
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